A female client is treated for trichomoniasis with metronidazole (Flagyl). The nurse instructs the client that:
A. Her partner does not need treatment.
B. She should avoid alcohol during treatment and for 24 hours after completion of the drug.
C. She should discontinue oral contraceptive use during this treatment.
D. The medication should not alter the colour of the urine.
Answer:- B. She should avoid alcohol during treatment and for 24 hours after completion of the drug.
Trichomoniasis is a sexually transmitted infection caused by the parasite Trichomone vaginalius. Metronidazole (Flagyl) is an antibiotic used for treating this disease. When taking metronidazole, it should be strictly avoided to consume alcohol during treatment and even after completing the medication course for at least 24 hours.
There are a couple of reasons why alcohol should be avoided with metronidazole use:
First, metronidazole and alcohol both affect liver enzymes that the body uses to process medication. Such combinations can lead to a concentration of metronidazole in the body, which may be intensified and result in more severe side effects.
Second, mixing metronidazole and alcohol can cause a very unpleasant disulfiram-like reaction. Flushing, headache, nausea, vomiting, sweating and increased heart rate are involved in this reaction. This happens because metronidazole and its metabolites interfere with how acetaldehyde – a compound generated during alcoholic breakdown- is handled. These adverse effects occur as a result of the accumulation of acetaldehyde.
Hence, healthcare practitioners strongly recommend that patients under metronidazole treatment avoid any alcohol drinking throughout the course of receiving this antibiotic and one full day after its completion. This measure will aid in avoiding possible complications as a result of interaction with alcohol and this specific antibiotic.
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